Hemophilia Dosing and Cost - 1
ALPHANATE offers savings when treating patients with hemophilia A
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Hemophilia Dosing and Cost - 2
|Hemorrhagic event||Dosage (IU FVIII:C/kg body weight)|
|Minor hemorrhage Large bruises, significant cuts or scrapes, uncomplicated joint hemorrhage||Bring FVIII:C to 30% (15 IU FVIII/kg BID) until hemorrhage stops and healing is achieved (1 to 2 days)|
|Moderate hemorrhage Nose, mouth, and gum bleeds; dental extractions; hematuria||Bring FVIII:C to 50% (25 IU FVIII/kg BID) until healing is achieved (2 to 7 days on average)|
|Major hemorrhage Joint hemorrhage, muscle hemorrhage, major trauma, hematuria, intracranial and intraperitoneal bleeding||Bring FVIII:C to 80% to 100% for at least 3 to 5 days(40 to 50 IU FVIII/kg BID).Maintain at 50% (25 IU FVIII/kg BID) until healing is achieved. Major bleeds may require treatment for up to 10 days; intracranial bleeds up to 6 months|
|Surgery||Prior to surgery, bring level of FVIII:C to 80% to 100%(40 to 50 IU FVIII/kg).Maintain at 60% to 100% (30 to 50 IU FVIII/kg BID) for the next 7 to 10 days or until healing is achieved|
Make the most of - 2
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Optimizing treatment with WAPPS-Hemo
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