ALPHANATE product design, storage, and administration
ALPHANATE packaging is designed with the unique needs of your high-volume FVIII users in mind
- ALPHANATE is the only FVIII/VWF complex to offer the convenience of a large 2000-IU vial size with low diluent volume1
- The availability of a large 2000-IU vial size with low diluent volume may provide greater convenience in the form of less volume, fewer syringes, and shorter daily infusion time
Five convenient vial sizes with low reconstitution volume1
|Potency||Diluent size||NDC number|
|250 IU FVIII range||5 mL||68516-4601-1 or 68516-4611-1|
|500 IU FVIII range||5 mL||68516-4602-1 or 68516-4612-1|
|1000 IU FVIII range||10 mL||68516-4603-2 or 68516-4613-2|
|1500 IU FVIII range||10 mL||68516-4604-2 or 68516-4614-2|
|2000 IU FVIII range||10 mL||68516-4609-2 or 68516-4615-2|
How to store ALPHANATE
ALPHANATE is stable for 3 years, up to the expiration date printed on its label, provided that the storage temperature does not exceed 77°F (25°C). Do not freeze.1
Easy reconstitution of ALPHANATE
To make reconstitution easier for your patients, a Mix2Vial® device is included in every package of ALPHANATE.
Watch the Mix2Vial® reconstitution demonstration below.
Administration of ALPHANATE
ALPHANATE is for intravenous use only after reconstitution. Patients should use plastic disposable syringes. ALPHANATE should not be refrigerated after reconstitution. Reconstituted ALPHANATE may be stored at room temperature (not to exceed 30°C) prior to administration, but must be administered intravenously within 3 hours. Discard unused contents into the appropriate safety container. ALPHANATE should not be administered at a rate exceeding 10 mL/min.
DemoPacks are available for instructional purposes to help patients, parents, and nurses familiarize themselves with this easy-to-use transfer set. Contents of the DemoPacks include: empty product vial, diluent (sterile water for injection USP 5 mL), and Mix2Vial® 15-µm filter transfer set.
FVIII=factor FVIII; VWF=von Willebrand factor.